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Cannabidiol CBD may have some health benefits, and it may also pose risks. Products containing the compound are now legal in many American states where marijuana is not. This article will explain what CBD is, its possible health benefits, how to use it, potential risks, and issues surrounding its legality in the United States. CBD is one of many compounds, known as cannabinoids, in the cannabis plant. Researchers have been looking at the possible therapeutic uses of CBD. The concentrations and the uses of these oils vary.
THC creates a mind-altering "high" when a person smokes it or uses it in cooking. This is because THC breaks down when we apply heat and introduce it into the body. Unlike THC, it is not psychoactive. This means that CBD does not change a person's state of mind when they use it.
However, CBD does appear to produce significant changes in the body, and some research suggests that it has medical benefits. The least processed form of the cannabis plant is hemp. Hemp contains most of the CBD that people use medicinally. Hemp and marijuana come from the same plant, Cannabis sativa , but the two are very different. Over the years, marijuana farmers have selectively bred their plants to contain high levels of THC and other compounds that interested them, often because the compounds produced a smell or had another effect on the plant's flowers.
However, hemp farmers have rarely modified the plant. These hemp plants are used to create CBD oil. The human body produces certain cannabinoids on its own. It also has two receptors for cannabinoids, called the CB1 receptors and CB2 receptors. The CB1 receptors in the brain deal with coordination and movement, pain, emotions, and mood, thinking, appetite, and memories, and other functions. THC attaches to these receptors. CB2 receptors are more common in the immune system. They affect inflammation and pain.
People tend to use prescription or over-the-counter drugs to relieve stiffness and pain, including chronic pain. Authors of a study published in the Journal of Experimental Medicine found that CBD significantly reduced chronic inflammation and pain in some mice and rats. The researchers suggested that the non-psychoactive compounds in marijuana, such as CBD, could provide a new treatment for chronic pain. Some promising evidence suggests that CBD use may help people to quit smoking.
A pilot study published in Addictive Behaviors found that smokers who used inhalers containing CBD smoked fewer cigarettes than usual and had no further cravings for nicotine. A similar review, published in Neurotherapeutics found that CBD may be a promising treatment for people with opioid addiction disorders.
The researchers noted that CBD reduced some symptoms associated with substance use disorders. These included anxiety , mood-related symptoms, pain, and insomnia. More research is necessary, but these findings suggest that CBD may help to prevent or reduce withdrawal symptoms. After researching the safety and effectiveness of CBD oil for treating epilepsy, the FDA approved the use of CBD Epidiolex as a therapy for two rare conditions characterized by epileptic seizures in The types of seizures that characterize LGS or DS are difficult to control with other types of medication.
The FDA specified that doctors could not prescribe Epidiolex for children younger than 2 years. A physician or pharmacist will determine the right dosage based on body weight. Authors of a review noted that CBD has anti-seizure properties and a low risk of side effects for people with epilepsy.
Findings suggested that CBD may also treat many complications linked to epilepsy, such as neurodegeneration, neuronal injury, and psychiatric diseases. Another study, published in Current Pharmaceutical Design, found that CBD may produce effects similar to those of certain antipsychotic drugs, and that the compound may provide a safe and effective treatment for people with schizophrenia.
However, further research is necessary. Some researchers have found that CBD may prove to combat cancer. Authors of a review published in the British Journal of Clinical Pharmacology found evidence that CBD significantly helped to prevent the spread of cancer. The researchers also noted that the compound tends to suppress the growth of cancer cells and promote their destruction. They pointed out that CBD has low levels of toxicity.
They called for further research into its potential as an accompaniment to standard cancer treatments. Doctors often advise people with chronic anxiety to avoid cannabis, as THC can trigger or amplify feelings of anxiousness and paranoia. However, authors of a review from Neurotherapeutics found that CBD may help to reduce anxiety in people with certain related disorders. According to the review, CBD may reduce anxiety-related behaviors in people with conditions such as:.
The authors noted that current treatments for these disorders can lead to additional symptoms and side effects, which can cause some people to stop taking them. No further definitive evidence currently links CBD to adverse effects, and the authors called for further studies of the compound as a treatment for anxiety. Type 1 diabetes results from inflammation that occurs when the immune system attacks cells in the pancreas. Research published in by Clinical Hemorheology and Microcirculation found that CBD may ease this inflammation in the pancreas.
This may be the first step in finding a CBD-based treatment for type 1 diabetes. A paper presented in the same year in Lisbon, Portugal, suggested that CBD may reduce inflammation and protect against or delay the development of type 1 diabetes.
Acne treatment is another promising use for CBD. The condition is caused, in part, by inflammation and overworked sebaceous glands in the body. A study published by the Journal of Clinical Investigation found that CBD helps to lower the production of sebum that leads to acne, partly because of its anti-inflammatory effect on the body.
Despite the modern-day stigma, cannabis and cannabinoids have been used for centuries as plant medicines and have a lot of potential to help people all over the world, which is just one more reason to stay up-to-date on the science and policy surrounding this pretty miraculous plant!
Have more questions about cannabinoids? Here's what doctors have to say about CBD oil. Food has the power to create a happier and healthier world. Celebrity Nutritionist Kelly LeVeque will show you how. Integrative Health integrative health. Group 8 Created with Sketch.
By Gretchen Lidicker mbg Health Editor. Group 7 Created with Sketch. Group 9 Created with Sketch. Group 10 Created with Sketch. Group 11 Created with Sketch. Email Created with Sketch.
Group 4 Created with Sketch. The differences between the cannabinoids. The benefits of cannabinoids. CBD oil versus hemp oil. Gretchen Lidicker mbg Health Editor. Originally from Sedona, Arizona, she has a Caroline Muggia 13 minutes ago. Still, it is important to try to understand the reasons for the lack of well-controlled clinical trials of CBD including: Furthermore, the opportunity to gather important information on clinical outcomes through practical non-randomized trials for patients using CBD products available in state marijuana dispensaries is complicated by the variable quality and purity of CBD from these sources.
Ongoing CBD Research The NIH recognizes the need for additional research on the therapeutic effects of CBD and other cannabinoids, and supports ongoing efforts to reduce barriers to research in this area.
NIH is currently supporting a number of studies on the therapeutic effects as well as the health risks of cannabinoids. These include studies of the therapeutic value of CBD for: For example, studies related to epilepsy will likely be funded by the National Institute of Neurological Disorders and Stroke or by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, while studies related to schizophrenia will likely be funded by the National Institute on Mental Health.
Conclusion There is significant preliminary research supporting the potential therapeutic value of CBD, and while it is not yet sufficient to support drug approval, it highlights the need for rigorous clinical research in this area. There are barriers that should be addressed to facilitate more research in this area. We appreciate the opportunity to testify on the potential use of CBD for therapeutic purposes.
Thank you again for inviting me here today, and I look forward to any questions you may have. If you are pregnant, nursing, taking medications, or have a medical condition, consult your physician before using this product. The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease. Click here to find evidence of a test, analysis, research, or study describing the benefits, performance or efficacy of CBD based on the expertise of relevant professionals.
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